According to Mississippi Highway Patrol, a pedestrian was struck and killed on US 49 just north of Magee.
It happened just before 8 p.m. Friday when a man ran across the northbound lane as a Chevrolet Tahoe was traveling north, according to authorities.
The victim was identified as 39-year-old Eric Lee, who was a patient at Boswell Regional Center and was diagnosed with Autism, according to MHP.
Lee was killed on the scene.
The accident remains under investigation.